病情說明：口部過敏症候群 (Oral Allergy Syndrome, OAS)

上周五取得化驗報告，雖然未能與醫生會談，但按自己推斷，我應該是有 OAS。

這個周末讀了很多資訊，小結如下：

1. OAS與花粉症(hay fever)同源，都是因免疫系統對花粉蛋白(pollen protein)異常的反應。

2. 對堅果、水果、種子等過敏，都是因為這些食物表層都有與花粉蛋白類似的蛋白。

3. 普及性：高達70% 花粉症患者也有OAS

4. 高峯期：花粉症季節（春、夏）

5. 氣候因素：通常在潮濕地帶情況較輕，因為濕氣使花粉沉到地面，不能在空中飄揚

6. 由於致敏蛋白不耐熱，因此可進食加熱處理過的水果，亦即罐頭水果。
注意：加熱無法破壞堅果的致敏蛋白。

7. 治療：暫時沒有治療方法，但可靠抗敏藥和止痛藥減輕症狀

8. 某些清潔用品（如肥皂、洗頭水）及化妝品可含水解小麥蛋白(Hydrolyzed wheat protein)，也是一種致敏原。

Source: https://www.e-cep.org/articles/search_result.php?term=4&key=Food%20hypersensitivity

 

================= ENGLISH SUMMARY =================

A few notes on Oral Allergy Syndrome (OAS):

1. OAS is akin to hay fever, which is the over-reaction of the immune system to pollen protein.

2. The surface of nuts, fruits, seeds contains allergen protein similar to that of pollen.

3. Prevalence: up to 70% of individuals with hay fever would have OAS.

4. Peak season: hay fever season (spring, summer)

5. Climate factor: often less severe in humid regions, as the moist makes pollen sink.

6. Heat can destroy the protein allergen. Therefore, processed (canned) fruits are safe to eat.
N.B. Heat cannot destroy the protein allergen on nuts. 

7. Treatment: no known treatment. Antihisamine and painkillers can relieve the symptoms. 

8. Some cleaning products (e.g., soap, shampoo) and cosmetics may contain hydrolyzed wheat protein, which is also an allergen. 

Extended reading:

Wikipedia: https://en.wikipedia.org/wiki/Oral_allergy_syndrome 

Oxford leaflet: https://www.ouh.nhs.uk/patient-guide/leaflets/files/5537Poralallergy.pdf

Stanford fact sheet: https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&ved=2ahUKEwj5-9zMrajxAhX7BGMBHbz8DCcQFjAAegQIAxAD&url=https%3A%2F%2Fstanfordhealthcare.org%2Fcontent%2Fdam%2FSHC%2Fclinics%2Fmenlo-medical-clinic%2Fdocs%2FAllergy%2FOral%2520Allergy%2520Syndrome.pdf&usg=AOvVaw32bPfYlCoiDWua-HYf2N84